Beecher: Frankly, it sounds like you've covered the main points already.
You know the advantages and disadvantages of each. Now you have to decide what's right for you, and they type of diving you'll be doing.
There is no perfect suit. There is seldom even a "perfect suit" for YOU. What you have to do is decide which compromises you're willing to make.
If it helps any, I looked over the same information you did, and I ended up going with the CLX450. I did spend a lot of time wondering about the CF200, however, and even the TLS350. How important is fast drying time... to ME? How important is the heavy "wet weight" of the CF200... to ME? Will the 50/50 bring me the disadvantages of both, and the advantages of both?
In the end, I went with the "goldilocks" suit, the 450. I was saved the consternation over the 50/50 because I was on a budget. As it is, I think I made the right choice... I don't think the 350 would have been durable enough for me, and there are times that I find the 450 heavy enough as it is to want the CF200... although I do sometimes wonder. I sometimes wonder about the extra flexibility the 450 gives up over both alternatives, but I wouldn't want that to come with less durability. Having had the 450, however, I don't really see how the 50/50's neoprene legs would make such a huge difference... to ME. I'm glad I saved the money. And I'm glad I don't have to carry the extra lead the CF200 would require (even if it's not a huge amount more).
In an ideal world, I'd probably own all three: 350, 450 and CF200.

In THIS world, I'm very happy with my CLX450.
I did limit my choices to DUI (only after soul searching and some serious "almosts" with some really nice Bare suits... and today, the Fusion would be a serious monkey wrench in my decision-making), primarily because I was certain I wanted zip seals. Or at least the
option of zip seals. (I bought without to lower the initial cost of entry, and added them later... can't do that with other makes.)